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Kids First: Intersections of Cancer & SBD
Kids First Data Resource
Data Resource:  Kids First Data Resource
Point of Contact:  
Allison Heath,  
Project

About This Dataset
Birth defects and childhood cancer share biological pathways that are important for cell growth and division. We propose that sequencing pediatric patients suffering both conditions will allow us to discover the underlying genes and in turn advance our understanding of the causes of these devastating diseases.
Core Data Elements
Number of Cases
1,777
Case Sex
Female (868); Male (909)
Case Age At Diagnosis
0 to 4 years (799); 5 to 9 years (327); 10 to 14 years (247); 15 to 19 years (56); Pediatric and Young Adult (<40 years) (348)
Case Race
American Indian or Alaska Native (6); Asian (25); Black or African American (309); Other (49); White (1,061); Unknown (324)
Case Ethnicity
Not Reported (1,777)
Case Disease Diagnosis
Benign Neoplasm of Skin (146); Brain Cancer (104); Brain Neoplasm (93); Cancer of Cerebellum (71); Connective and Soft Tissue Neoplasm (61); Cryptorchidism (64); Lymphoid Leukemia (63); Melanocytic Nevus (82); Neurofibromatosis (70); Neurofibromatosis Type 1 (103); Other (920)
Case Proband
Yes (1,453); No (324)
Number of Samples
1,776
Sample Assay Method
Whole Genome Sequencing (1,776)
Additional Data Elements
DBGAP STUDY IDENTIFIER
DATA REPOSITORY
Grant Information
X01HL140544
Charts
Male (909); Female (868)
909Male